BS EN 17641:2022 Foodstuffs Standard

Standard Number: BS EN 17641:2022

Pages: 52

Released: 2022-09-16

ISBN: 978 0 539 14227 3

Name: Foodstuffs. Multimethod for the determination of aflatoxins, deoxynivalenol, fumonisins, ochratoxin A, T-2 toxin, HT-2 toxin and zearalenone by LC-MS/MS

Status: Standard

Overview

Introducing the BS EN 17641:2022 Foodstuffs Standard, a comprehensive and essential guide for the determination of multiple mycotoxins in foodstuffs using the advanced LC-MS/MS technique. This standard is a must-have for laboratories, food safety professionals, and regulatory bodies committed to ensuring the highest levels of food safety and quality.

Key Features

• Comprehensive Coverage: This standard provides detailed methodologies for the detection and quantification of a wide range of mycotoxins, including aflatoxins, deoxynivalenol, fumonisins, ochratoxin A, T-2 toxin, HT-2 toxin, and zearalenone.
• Advanced Analytical Technique: Utilizes Liquid Chromatography coupled with Tandem Mass Spectrometry (LC-MS/MS), a state-of-the-art technique known for its high sensitivity, specificity, and accuracy in mycotoxin analysis.
• Up-to-Date Information: Released on 2022-09-16, this standard incorporates the latest scientific advancements and regulatory requirements, ensuring that your laboratory practices are current and compliant.
• Detailed Protocols: Includes step-by-step procedures, calibration methods, and quality control measures to ensure reliable and reproducible results.
• Extensive Documentation: Spanning 52 pages, this standard provides exhaustive information, including sample preparation, instrument settings, and data interpretation guidelines.

Why Choose BS EN 17641:2022?

Mycotoxins are toxic secondary metabolites produced by certain fungi, posing significant health risks to humans and animals. The presence of these contaminants in foodstuffs can lead to severe health issues, including liver damage, immunosuppression, and even cancer. Therefore, accurate detection and quantification of mycotoxins are crucial for food safety and public health.

The BS EN 17641:2022 Foodstuffs Standard is designed to address these challenges by providing a robust and reliable multimethod for mycotoxin analysis. By adopting this standard, laboratories can ensure the highest levels of accuracy and consistency in their testing procedures, thereby safeguarding consumer health and meeting regulatory requirements.

Applications

This standard is applicable to a wide range of foodstuffs, including cereals, nuts, dried fruits, spices, and processed foods. It is particularly valuable for:

• Food Testing Laboratories: Ensuring accurate and reliable mycotoxin analysis to meet regulatory standards and protect consumer health.
• Food Manufacturers: Implementing rigorous quality control measures to prevent mycotoxin contamination and ensure product safety.
• Regulatory Bodies: Establishing and enforcing food safety standards to protect public health and maintain consumer confidence.
• Research Institutions: Conducting advanced studies on mycotoxin occurrence, toxicity, and mitigation strategies.

Technical Specifications

The BS EN 17641:2022 Foodstuffs Standard provides detailed technical specifications for the determination of mycotoxins using LC-MS/MS, including:

• Sample Preparation: Guidelines for homogenization, extraction, and cleanup procedures to ensure accurate and reproducible results.
• Instrument Settings: Recommended parameters for LC-MS/MS analysis, including column selection, mobile phase composition, and mass spectrometer settings.
• Calibration and Quantification: Procedures for preparing calibration standards, constructing calibration curves, and quantifying mycotoxins in samples.
• Quality Control: Measures to ensure the reliability and accuracy of analytical results, including the use of internal standards, method validation, and performance criteria.
• Data Interpretation: Guidelines for interpreting and reporting analytical results, including criteria for identifying and quantifying mycotoxins.

Benefits

Adopting the BS EN 17641:2022 Foodstuffs Standard offers numerous benefits, including:

• Enhanced Food Safety: Accurate detection and quantification of mycotoxins help prevent contaminated food products from reaching consumers, thereby protecting public health.
• Regulatory Compliance: Ensures that your laboratory practices meet the latest regulatory requirements and industry standards.
• Improved Accuracy and Reliability: Detailed methodologies and quality control measures ensure consistent and reliable analytical results.
• Increased Efficiency: Streamlined procedures and comprehensive guidelines help optimize laboratory workflows and reduce analysis time.
• Consumer Confidence: Demonstrating a commitment to food safety and quality helps build trust and confidence among consumers and stakeholders.

Conclusion

The BS EN 17641:2022 Foodstuffs Standard is an indispensable resource for laboratories, food manufacturers, regulatory bodies, and research institutions dedicated to ensuring the highest levels of food safety and quality. By providing a robust and reliable multimethod for the determination of mycotoxins using LC-MS/MS, this standard helps safeguard public health, meet regulatory requirements, and enhance consumer confidence.

Invest in the BS EN 17641:2022 Foodstuffs Standard today and take a significant step towards ensuring the safety and quality of your food products.

BS EN 17641:2022

This standard BS EN 17641:2022 Foodstuffs. Multimethod for the determination of aflatoxins, deoxynivalenol, fumonisins, ochratoxin A, T-2 toxin, HT-2 toxin and zearalenone by LC-MS/MS is classified in these ICS categories:

• 67.050 General methods of tests and analysis for food products

This document describes a method using isotopically labelled standards for the quantitative determination of aflatoxins B1, B2, G1, G2 and M1 (AFB1, AFB2, AFG1, AFG2 and AFM1), ochratoxin A (OTA), deoxynivalenol (DON), zearalenone (ZEN), T-2 and HT-2 toxins (T-2 and HT-2) and fumonisins B1 and B2 (FB1 and FB2) in foods by liquid chromatography (LC) coupled with tandem mass spectrometry (MS/MS). A specific immunoaffinity column (IAC) clean-up is needed for aflatoxins (AFs) and OTA in food intended for infants and young children (e.g. infant cereals, milk-based powders), in spices, in dried fruits and in nuts. The method has been validated through an intercollaborative study on different commodity groups: cereals and cereal-based products including food for infant and young children, nuts, spices, dried fruits and milk powder. The measuring range of each mycotoxin in these naturally contaminated and/or spiked food samples were: - AFB1: 0,085 7 µg/kg - 11,4 µg/kg; - AFB2: 0,079 2 µg/kg - 12,5 µg/kg; - AFG1: 0,062 8 µg/kg - 20,9 µg/kg; - AFG2: 0,052 0 µg/kg - 15,0 µg/kg; - AFM1: 0,034 2 µg/kg - 0,110 µg/kg; - OTA: 0,448 µg/kg - 17,2 µg/kg; - DON: 45,2 µg/kg - 743 µg/kg; - ZEN: 9,57 µg/kg - 131 µg/kg; - T-2: 10,3 µg/kg - 57,9 µg/kg; - HT-2: 9,50 µg/kg - 81,8 µg/kg; - FB1: 31,1 µg/kg - 4 260 µg/kg; - FB2: 44,2 µg/kg - 1 300 µg/kg. The measuring ranges of the method for each mycotoxin/matrix combination are given in Table 8.