BS EN ISO 13885-3:2021 Gel Permeation Chromatography (GPC) Water as Eluent

Standard Number: BS EN ISO 13885-3:2021

Pages: 32

Released: 2021-10-04

ISBN: 978 0 539 17264 5

Name: Gel Permeation Chromatography (GPC) Water as Eluent

Status: Standard

Overview

Introducing the BS EN ISO 13885-3:2021, a comprehensive standard dedicated to the methodology of Gel Permeation Chromatography (GPC) using water as the eluent. This standard is an essential resource for professionals in the field of analytical chemistry, providing detailed guidelines and protocols to ensure accurate and reliable results in GPC analysis.

Key Features

• Comprehensive Guidelines: This standard offers a thorough set of guidelines for conducting GPC with water as the eluent, ensuring that users can achieve consistent and reproducible results.
• Up-to-Date Information: Released on October 4, 2021, this standard incorporates the latest advancements and best practices in the field of GPC.
• Detailed Protocols: With 32 pages of detailed protocols, this standard covers every aspect of the GPC process, from sample preparation to data analysis.
• International Recognition: As an ISO standard, BS EN ISO 13885-3:2021 is recognized and respected worldwide, making it a valuable addition to any laboratory's reference library.

Benefits

Adopting the BS EN ISO 13885-3:2021 standard offers numerous benefits to laboratories and professionals involved in GPC analysis:

• Enhanced Accuracy: By following the standardized protocols, users can achieve higher accuracy in their GPC results, reducing the risk of errors and inconsistencies.
• Improved Reproducibility: Standardized methods ensure that results are reproducible across different laboratories and experiments, facilitating collaboration and comparison of data.
• Increased Efficiency: The detailed guidelines help streamline the GPC process, saving time and resources while maintaining high-quality results.
• Global Compliance: Compliance with an internationally recognized standard ensures that your laboratory meets global quality and regulatory requirements.

Who Should Use This Standard?

The BS EN ISO 13885-3:2021 standard is designed for a wide range of professionals and organizations, including:

• Analytical Chemists: Professionals involved in the analysis of polymers, biopolymers, and other macromolecules will find this standard invaluable for their work.
• Research Laboratories: Academic and industrial research laboratories conducting GPC analysis can benefit from the standardized protocols and guidelines.
• Quality Control Laboratories: Laboratories responsible for quality control and assurance can use this standard to ensure the accuracy and reliability of their GPC results.
• Regulatory Bodies: Regulatory agencies and organizations can reference this standard to establish and enforce quality and compliance requirements for GPC analysis.

Content Overview

The BS EN ISO 13885-3:2021 standard is divided into several sections, each covering a specific aspect of the GPC process:

• Introduction: An overview of the standard, its scope, and its intended use.
• Terminology: Definitions of key terms and concepts related to GPC and the use of water as the eluent.
• Methodology: Detailed protocols for sample preparation, instrument calibration, and GPC analysis.
• Data Analysis: Guidelines for interpreting and analyzing GPC data, including tips for troubleshooting common issues.
• Quality Control: Recommendations for maintaining the accuracy and reliability of GPC results through regular quality control measures.
• Appendices: Additional resources, including reference materials and supplementary information.

Why Choose BS EN ISO 13885-3:2021?

Choosing the BS EN ISO 13885-3:2021 standard for your GPC analysis needs offers several advantages:

• Expertly Developed: This standard has been developed by leading experts in the field of analytical chemistry, ensuring that it reflects the latest knowledge and best practices.
• Internationally Recognized: As an ISO standard, it is recognized and respected by professionals and organizations worldwide.
• Comprehensive Coverage: With 32 pages of detailed guidelines and protocols, this standard covers every aspect of the GPC process, providing a complete resource for users.
• Up-to-Date Information: Released in 2021, this standard incorporates the latest advancements and developments in GPC technology and methodology.

Conclusion

The BS EN ISO 13885-3:2021 standard is an essential resource for anyone involved in Gel Permeation Chromatography (GPC) using water as the eluent. With its comprehensive guidelines, detailed protocols, and international recognition, this standard provides the tools and information needed to achieve accurate, reliable, and reproducible results in GPC analysis. Whether you are an analytical chemist, a research laboratory, a quality control laboratory, or a regulatory body, the BS EN ISO 13885-3:2021 standard is a valuable addition to your reference library.

BS EN ISO 13885-3:2021

This standard BS EN ISO 13885-3:2021 Gel permeation chromatography (GPC) is classified in these ICS categories:

• 87.060.20 Binders

This document specifies the determination of the molar-mass distribution and the average molar mass values M_n (number average) and M_w (weight average) of polymers that are soluble in water by gel permeation chromatography (GPC).

NOTE Also known as size exclusion chromatography (SEC).

This method is applicable to neutral polymers and polyanions (e.g. polycarboxylates, polysaccharides, fully hydrolyzed polyvinyl alcohols and high-molecular polyethylene oxides). It is not applicable to polycations [e.g. polyvinylpyrrolidone, polyvinylpyridine, salts of poly(diallyl‑N,N‑dimethyl‑azacyclopentane), chitosan].

Despite good solubility in the mobile phase and even though the chromatograms obtained show good repeatability, it is possible that this method cannot be used with certain polymer types because of specific interactions (e.g. adsorption) within the sample/eluent/column system (see also Clause 12).

The conditions specified in this document are not applicable to the GPC analysis of polymer samples with M_w values greater than 10⁶ g/mol and/or polymers with elution limits outside the calibration range (see 7.6 and Annex C).

This document includes no correction methods (e.g. for the elimination of peak broadening). If absolute molar mass values are required, an absolute method (e.g. membrane osmometry for M_n or light scattering for M_w) can be used.