BS EN ISO 17099:2024 - Radiological Protection Standard

Standard Number: BS EN ISO 17099:2024

Pages: 46

Released: 2024-06-28

ISBN: 978 0 539 19945 1

Name: Radiological protection. Performance criteria for laboratories using the cytokinesis-block micronucleus (CBMN) assay in peripheral blood lymphocytes for biological dosimetry

Status: Standard

Overview

Introducing the BS EN ISO 17099:2024, a comprehensive standard dedicated to radiological protection. This essential document sets forth the performance criteria for laboratories utilizing the cytokinesis-block micronucleus (CBMN) assay in peripheral blood lymphocytes for biological dosimetry. With its release on June 28, 2024, this standard is poised to become a cornerstone in the field of radiological protection, ensuring accuracy, reliability, and consistency in biological dosimetry practices.

Key Features

• Comprehensive Guidelines: The standard provides detailed performance criteria for laboratories, ensuring that the CBMN assay is conducted with the highest level of precision and reliability.
• Enhanced Radiological Protection: By adhering to the guidelines set forth in this standard, laboratories can significantly improve their radiological protection measures, safeguarding both personnel and the environment.
• International Recognition: As an ISO standard, BS EN ISO 17099:2024 is recognized globally, facilitating international collaboration and standardization in radiological protection practices.
• Up-to-Date Information: Released in 2024, this standard incorporates the latest advancements and research in the field, ensuring that laboratories are equipped with the most current and effective methodologies.

Why Choose BS EN ISO 17099:2024?

The BS EN ISO 17099:2024 standard is an invaluable resource for laboratories involved in biological dosimetry. Here are some compelling reasons to adopt this standard:

• Accuracy and Precision: The standard outlines stringent performance criteria, ensuring that the CBMN assay is performed with the highest level of accuracy and precision. This is crucial for obtaining reliable dosimetry results.
• Consistency: By following the guidelines in this standard, laboratories can achieve consistent results, which is essential for comparing data across different studies and institutions.
• Compliance: Adhering to an internationally recognized standard helps laboratories comply with regulatory requirements and enhances their credibility in the scientific community.
• Safety: The standard emphasizes radiological protection, helping laboratories implement effective safety measures to protect personnel from radiation exposure.

Detailed Content

The BS EN ISO 17099:2024 standard spans 46 pages, offering a thorough exploration of the performance criteria for the CBMN assay. Key sections include:

• Introduction: An overview of the importance of radiological protection and the role of the CBMN assay in biological dosimetry.
• Performance Criteria: Detailed guidelines on the performance criteria for laboratories, including sample preparation, assay execution, and result interpretation.
• Quality Control: Recommendations for quality control measures to ensure the reliability and accuracy of the CBMN assay.
• Safety Protocols: Guidelines for implementing radiological protection measures to safeguard laboratory personnel.
• Appendices: Additional resources and references to support the implementation of the standard.

Who Should Use This Standard?

The BS EN ISO 17099:2024 standard is designed for a wide range of professionals and institutions involved in radiological protection and biological dosimetry, including:

• Laboratories: Research and clinical laboratories conducting the CBMN assay for biological dosimetry.
• Regulatory Bodies: Organizations responsible for setting and enforcing radiological protection standards.
• Healthcare Providers: Medical professionals involved in radiation therapy and radiological diagnostics.
• Academic Institutions: Universities and research institutions conducting studies on radiological protection and dosimetry.

Conclusion

The BS EN ISO 17099:2024 standard is an essential tool for any laboratory or institution involved in radiological protection and biological dosimetry. By providing comprehensive performance criteria for the CBMN assay, this standard ensures that laboratories can achieve accurate, reliable, and consistent results, ultimately enhancing radiological protection measures and safeguarding both personnel and the environment. With its international recognition and up-to-date information, the BS EN ISO 17099:2024 standard is a must-have resource for professionals in the field.

BS EN ISO 17099:2024

This standard BS EN ISO 17099:2024 Radiological protection. Performance criteria for laboratories using the cytokinesis-block micronucleus (CBMN) assay in peripheral blood lymphocytes for biological dosimetry is classified in these ICS categories:

• 13.280 Radiation protection
• 13.280 Radiation protection

This document gives guidance on a)       confidentiality of personal information for the customer and the laboratory, b)       laboratory safety requirements, c)        calibration sources and calibration dose ranges useful for establishing the reference dose-response curves that contribute to the dose estimation from CBMN assay yields and the detection limit, d)       performance of blood collection, culturing, harvesting, and sample preparation for CBMN assay scoring, e)       scoring criteria, f)         conversion of micronucleus frequency in BNCs into an estimate of absorbed dose, g)       reporting of results, h)       quality assurance and quality control, and i)         informative annexes containing sample instructions for customers, sample questionnaire, a microscope scoring data sheet, and a sample report. This document excludes methods for automated scoring of CBMN.