BS ISO 21470:2020 - Infant Formula and Adult Nutritionals

Discover the comprehensive standard for the simultaneous determination of essential vitamins in infant formula and adult nutritionals with the BS ISO 21470:2020. This standard is an indispensable resource for professionals in the food and nutrition industry, providing a detailed methodology for the accurate measurement of total vitamins B₁, B₂, B₃, and B₆.

Overview

The BS ISO 21470:2020 standard outlines a precise and reliable method for the determination of key B vitamins using enzymatic digestion followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS). This method ensures the accurate quantification of these essential nutrients, which are crucial for maintaining optimal health and development in both infants and adults.

Key Features

• Standard Number: BS ISO 21470:2020
• Pages: 38
• Released: 2020-11-05
• ISBN: 978 0 580 96301 8
• Status: Standard

Importance of Vitamins B₁, B₂, B₃, and B₆

Vitamins B₁ (Thiamine), B₂ (Riboflavin), B₃ (Niacin), and B₆ (Pyridoxine) play vital roles in energy production, brain function, and the synthesis of neurotransmitters. Ensuring the correct levels of these vitamins in nutritional products is essential for supporting metabolic processes and overall health.

Vitamin B₁ (Thiamine)

Thiamine is crucial for carbohydrate metabolism and nerve function. It helps convert nutrients into energy and is essential for the proper functioning of the heart, muscles, and nervous system.

Vitamin B₂ (Riboflavin)

Riboflavin is important for energy production and the metabolism of fats, drugs, and steroids. It also plays a key role in maintaining healthy skin and eyes and is involved in the conversion of tryptophan to niacin.

Vitamin B₃ (Niacin)

Niacin is involved in DNA repair, the production of steroid hormones in the adrenal gland, and the metabolism of carbohydrates, fats, and proteins. It is also essential for maintaining healthy skin and nerves.

Vitamin B₆ (Pyridoxine)

Pyridoxine is vital for amino acid metabolism, neurotransmitter synthesis, and the production of hemoglobin. It also supports immune function and the regulation of blood glucose levels.

Methodology

The BS ISO 21470:2020 standard employs a sophisticated analytical technique combining enzymatic digestion with LC-MS/MS. This method provides high sensitivity and specificity, allowing for the precise quantification of vitamins even in complex matrices such as infant formula and adult nutritional products.

Enzymatic Digestion

Enzymatic digestion is used to release the vitamins from the food matrix, ensuring that they are in a form suitable for analysis. This step is crucial for achieving accurate and reproducible results.

LC-MS/MS Analysis

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a powerful analytical technique that separates and quantifies the vitamins with high precision. This method is renowned for its ability to handle complex samples and provide detailed information on the composition of nutritional products.

Applications

The BS ISO 21470:2020 standard is applicable to a wide range of products, including:

• Infant formula
• Adult nutritional supplements
• Fortified foods and beverages
• Clinical nutrition products

Benefits

Implementing the BS ISO 21470:2020 standard offers numerous benefits, including:

• Enhanced Product Quality: Ensures that nutritional products meet the highest standards of quality and safety.
• Regulatory Compliance: Helps manufacturers comply with international regulations and standards for nutritional labeling.
• Consumer Confidence: Provides assurance to consumers that products contain the stated levels of essential vitamins.
• Research and Development: Supports the development of new and improved nutritional products.

Conclusion

The BS ISO 21470:2020 standard is an essential tool for professionals in the food and nutrition industry. By providing a reliable method for the determination of total vitamins B₁, B₂, B₃, and B₆, it ensures the production of high-quality nutritional products that meet the needs of consumers worldwide. Embrace this standard to enhance your product offerings and ensure compliance with international nutritional guidelines.

BS ISO 21470:2020

This standard BS ISO 21470:2020 Infant formula and adult nutritionals. Simultaneous determination of total vitamins B₁, B₂, B₃ and B₆. Enzymatic digestion and LC-MS/MS is classified in these ICS categories:

• 67.050 General methods of tests and analysis for food products

This document specifies a method for the simultaneous quantitative determination of four water-soluble vitamins in infant formula and related nutritional products, including relevant forms of vitamins B₁, B₂, B₃ and B₆ by enzymatic digestion and UHPLC-MS/MS. This document is not intended to be used on products where vitamins have not been added.