BS ISO 22104:2021 - Water Quality: Determination of Microcystins

Ensure the highest standards of water quality with the BS ISO 22104:2021 standard, a comprehensive guide for the determination of microcystins using advanced liquid chromatography and tandem mass spectrometry (LC-MS/MS) techniques. Released on July 7, 2021, this standard is an essential resource for laboratories, environmental agencies, and water quality professionals dedicated to maintaining safe and clean water supplies.

Key Features

• Standard Number: BS ISO 22104:2021
• Pages: 42
• Release Date: July 7, 2021
• ISBN: 978 0 580 52385 4
• Status: Standard

Why Choose BS ISO 22104:2021?

Microcystins are potent toxins produced by certain freshwater cyanobacteria, posing significant health risks to humans and animals. The BS ISO 22104:2021 standard provides a robust methodology for accurately detecting and quantifying these toxins, ensuring that water sources are safe for consumption and use. By implementing this standard, you can:

• Enhance Public Health: Protect communities from the harmful effects of microcystins by ensuring water quality meets international safety standards.
• Improve Analytical Accuracy: Utilize state-of-the-art LC-MS/MS techniques for precise and reliable detection of microcystins.
• Comply with Regulations: Meet regulatory requirements and guidelines for water quality monitoring and safety.

Comprehensive Coverage

Spanning 42 pages, the BS ISO 22104:2021 standard offers detailed instructions and guidelines for the determination of microcystins. It covers all aspects of the analytical process, from sample collection and preparation to data analysis and interpretation. This ensures that users have a complete understanding of the methodology and can implement it effectively in their operations.

Advanced Methodology

The standard employs liquid chromatography and tandem mass spectrometry (LC-MS/MS), a cutting-edge analytical technique known for its sensitivity and specificity. This method allows for the detection of microcystins at very low concentrations, providing a high level of confidence in the results. The use of LC-MS/MS also enables the simultaneous analysis of multiple microcystin variants, offering a comprehensive assessment of water quality.

Global Relevance

As a part of the ISO standards, BS ISO 22104:2021 is recognized and respected worldwide. It provides a consistent framework for water quality assessment, facilitating international collaboration and data sharing. By adopting this standard, organizations can align their practices with global best practices, enhancing their credibility and reputation in the field of water quality management.

Who Should Use This Standard?

The BS ISO 22104:2021 standard is designed for a wide range of users, including:

• Environmental Laboratories: Equip your lab with the latest methodologies for water quality testing and analysis.
• Water Treatment Facilities: Ensure the safety and quality of treated water by monitoring for microcystins.
• Regulatory Agencies: Establish and enforce water quality standards to protect public health.
• Research Institutions: Conduct cutting-edge research on water quality and toxin detection.

Conclusion

In an era where water quality is of paramount importance, the BS ISO 22104:2021 standard stands as a vital tool for ensuring the safety and purity of water supplies. By providing a detailed and reliable method for the determination of microcystins, this standard empowers professionals to protect public health and uphold the highest standards of environmental safety. Invest in the BS ISO 22104:2021 standard today and take a proactive step towards safeguarding our most precious resource.

BS ISO 22104:2021

This standard BS ISO 22104:2021 Water quality. Determination of microcystins. Method using liquid chromatography and tandem mass spectrometry (LC-MS/MS) is classified in these ICS categories:

• 13.060.50 Examination of water for chemical substances

This document specifies a method for the quantification of twelve microcystin variants (microcystin-LR, -LA, -YR, -RR, -LY, -WR, -HtyR, -HilR, -LW, -LF, [Dha⁷]-microcystin-LR, and [Dha⁷]-microcystin-RR) in drinking water and freshwater samples between 0,05 µg/l to 1,6 µg/l. The method can be used to determine further microcystins, provided that analytical conditions for chromatography and mass spectrometric detection has been tested and validated for each microcystin. Samples are analysed by LC-MS/MS using internal standard calibration.

This method is performance based. The laboratory is permitted to modify the method, e.g. increasing direct flow injection volume for low interference samples or diluting the samples to increase the upper working range limit, provided that all performance criteria in this method are met.

Detection of microcystins by high resolution mass spectrometry (HRMS) as an alternative for tandem mass spectrometry (MS/MS) is described in Annex A.

An alternative automated sample preparation method based on on-line solid phase extraction coupled to liquid chromatography is described in Annex B.

When instrumental sensitivity is not sufficient to reach the method detection limits by direct flow injection, a solid phase extraction clean-up and concentration step is described in Annex C.